Introduction

The department of Transfusion Medicine and Blood Bank at SSPH & PGTI is committed to provide safe blood and blood components support to patients. The department endeavours to provide blood components such as packed red cells, platelets concentrates, fresh frozen plasma, cryoprecipitate, single donor apheresis platelets, granulocytes and peripheral blood hematopoietic progenitor cells. Safety of blood and blood components are ensured with careful donor interview and examination with screening of donated blood for HIV 1 & 2, Hepatitis B & C, Malaria and Syphilis using appropriate technology.

Name of the Faculty

Dr Seema Dua

Designation: Additional Professor
Qualification: MBBS, MD (Pathology)
Special Interest: Blood Component Therapy, Transfusion Transmitted Ing=fection Screening

Dr Satyam Arora

Designation: Associate Professor-cum/or Senior Consultant
Qualification: MBBS, MD (Transfusion Medicine)
Special Interest: Clinical Transfusion, Immunohematology, Cellular Therapy, Clinical Apheresis”

Patient Services

  1. Blood Component Therapy

    2. The department is committed to provide 24 x 7 availability of blood components such as Packed Red Blood Cells (PRBC), Platelets Concentrates (PC), Fresh Frozen Plasma (FFP), Cryoprecipitate, Cryo Poor Plasma (CPP), Single Donor platelets and plasma products, Granulocytes and buffy costs, Hematopoietic Stem cells

  2. Specialized Blood Components for Paediatric Transfusion Practices:

    3. Reconstituted Whole Blood (Exchange Transfusion), Paediatric PRBC units for transfusing neonates

  3. Specialized Testing for Blood Components:

    4. The blood products at SSPH & PGTI are tested for Anti HIV 1 & 2, HBsAg, Anti HCV, Malaria and Syphilis. In addition to the above mandatory testing all the blood components are also tested for Anti HBc (core). The compatibility testing for these components are done on Gel technology.

  4. Immunohematology Lab

    5. The Department has established a state of art immunohematology lab to provide all extensive testing for rare blood groups and the alloantibodies. In addition the lab routinely provide extensive work up for AIHA, Cold Agglutinins and PNH.

  5. Therapeutic Cytapheresis

    6. The department also provides therapeutic cervices such as therapeutic phlebotomy for polycythemia/ haemochromatosis, therapeutic plasma exchange, therapeutic cytapheresis, and peripheral stem cell harvests.

  6. Quality Assurance

    7. The department participates in quarterly BEQAS (Blood Bank External Quality Assurance Scheme) to ensure adequate quality of its blood components and testing facility.

  7. Hemovigillance

    8. The department is empanelled for reporting to Hemovigillance Program of India and reporting all patient transfusion reactions and donor adverse reaction to the national program.

  8. Thalassemia and Hemophilia Center

    9. The department provides regular transfusion support to the institutional Thalassemia and Hemophilia center.

Academic Events

Courses/ Training offered

DNB in Immuno Hematology and Blood Transfusion (IHBT)- Annual intake of 2

Educative Material

  1. Guidelines for Handling Blood and Blood Components (2023)
  2. First Annual SSPH & PGTI update on Paediatric Transfusion medicine Practice (Souvenir 2017)
  3. Standard Operating Procedure (SOP) in Basics in Immunohematology for Blood Banks (in Hindi)

Research Projects

COVID Related

S. No. Project Type of work Type (Institutional/ Regional/ National/ International)
1 A Phase II, Open Label, Randomized Controlled Trial to Assess the Safety and Efficacy of Convalescent Plasma to Limit COVID-19 Associated Complications in Moderate Disease (PLACID Trial) Original Work
Extra Mural Project		 National
2 Human Monoclonal and Polyclonal Antibodies to COVID-19 Original Work
Extra Mural Project		 International
3 Awareness toward need for regular blood donation and attitude of voluntary blood donors blood donation during covid 19 pandemic Original Work National
4 Pediatric COVID-19 Convalescent Plasma Use Registry Study Original Work International
5 Seroprevalence of antibodies to SARS-CoV-2 among admitted children at a tertiary pediatric care center in state of Uttar Pradesh Original Work Institutional
6 Characterization and Seroprevalence of antibodies among the SARS-CoV-2 Convalescent Plasma Donors Original Work Institutional

NON COVID

S. No. Project Type of work Type (Institutional/ Regional/ National/ International)
1 Survey of Blood Centers providing Transfusion support to Neonatal and Pediatric group of patients across India Original Work National
2 Incidence of TTI reactivity in Parental versus Non-Parental Replacement Blood Donors: An experience from a Pediatric Tertiary care center from North India Original Work Institutional
3 Indication of Transfusion of Blood and Blood components for Pediatric and Neonatal group of patients in India Original Work National
4 Red Cell Transfusions Support in Pediatric Blood Cancers at a Tertiary Pediatric Care Center Original Work Institutional
5 Validation of Syringe Based Small Volume Transfusion Set Original Work Institutional

Publications

Pubmed Link:- https://www.ncbi.nlm.nih.gov/pubmed/?term=Satyam+Arora

  1. Arora S, Marwaha N, Dhawan HK, Rao KLN. Dedicated donor unit transfusions reduce donor exposure in paediatric surgery patients. Asian J Transfus Sci 2017 July 11(2): 124-130.Goyal A, Dua S, Arora S. Naturally Occurring Anti-S Antibody in a Blood Donor: Screening using Panel Cells. Global J Transfusion Med AATM Jan-Jun, 2020;1:101-103.
  2. Arora S, Majhail NS, Liu H. Hematopoietic Progenitor Cell Mobilization for Autologous Stem Cell Transplantation in Multiple Myeloma in Contemporary Era. Clinical Lymphoma, Myeloma & Leukemia April 2019.
  3. Radhakrishnan N, Dua S, Arora S. IgA-Mediated Autoimmune Hemolytic Anemia in an Infant. Transfus Apher Sci. 2019. https://doi.org/10.1016/j.transci.2019.102695
  4. Upadhyaya GK, Jain VK, Arora S, Arya RK, Doda V. Role of Autologous Platelet Rich Plasma Intraarticular Injection in Primary Osteoarthritis of the Knee Joint. Scholar Journal of Applied Medical Science (SJAMS), Oct 2018; 6(10): 3779-3783.
  5. Arora S, Al-Riyami AZ, Hutchinson T, Cecile Toly-Ndour, Tung JP, Ji Y, Uyogya S. Young Professional Council with the International Society of Blood Transfusion. Global J Transfusion Med AATM Jan-Jun 2020; 1:104-107.
  6. Dhiman Y, Patidar GK, Arora S. Covid-19 pandemic response to challenges by blood transfusion services in India: a review report. ISBT Science Series (2020) 0, 1-9. DOI: 10.1111/voxs.12563
  7. Agarwal A, Mukherjee A, Kumar G, Chatterjee P, Bhatnagar T, Malhotra P; PLACID Trial Collaborators. Convalescent plasma in the management of moderate covid-19 in adults in India: open label phase II multicentre randomised controlled trial (PLACID Trial). BMJ. 2020 Oct 22;371:m3939. doi: 10.1136/bmj.m3939.
  8. Shankar R, Radhakrishnan N, Dua S, Arora S, Rana M, Sahu DK, Rai S, Gupta DK. Convalescent plasma to aid in recovery of COVID-19 pneumonia in a child with acute lymphoblastic leukemia. Transfus Apher Sci. 2020 Sep 24:102956. doi: 10.1016/j.transci.2020.102956. Epub ahead of print. PMID: 32994125.
  9. Shukla U, Bhakhri B, Arora S, Jain M, Jain V, Dua S, Singh DK, Gupta DK. Use of Convalescent Plasma for managing severe COVID-19 infection in 2 months old Infant. Accepted for publication with ISBT Science Series
  10. Goel R, Bloch EM, Pirenne F, Al-Riyami Arwa, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar P, Arora S et al. ABO blood group and COVID‐19: a review on behalf of the ISBT COVID‐19 working group. https://doi.org/10.1111/vox.13076. Vox Sanguinis 2021.
  11. Nayak K, Gottimukkala K, Kumar S, Reddy ES, Edara VV, Kauffman R, Floyd K, Mantus G, Savargaonkar D, Goel PK, Arora S. et al. Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India. Virology. 2021 Mar 5;558:13-21. doi: 10.1016/j.virol.2021.02.002. Epub ahead of print. PMID: 33706207; PMCID: PMC7934698.
  12. Wendel S, Land K, Devine DV, Daly J, Bazin R, Tiberghien P, Lee CK, Arora S, Patidar GK, Khillan K, Smid WM, Vrielink H, Oreh A, Al-Riyami AZ, Hindawi S, Vermeulen M, Louw V, Burnouf T, Bloch EM, Goel R, Townsend M, So-Osman C. Lessons learned in the collection of convalescent plasma during the COVID-19 pandemic. Vox Sang. 2021 Mar 27. doi: 10.1111/vox.13096. Epub ahead of print. PMID: 33772791.
  13. Basavarajegowda A, Bajpai M, Arora S, Maheshwari A, Dua S, Sahoo D. Survey based cross-sectional study to analyse the variation of practices at blood centres during COVID-19 pandemic in India. Transfus Apher Sci. 2021 Apr 14:103131. doi: 10.1016/j.transci.2021.103131. Epub ahead of print. PMID: 33865716.
  14. Dua S, Arora S, Manocha H, Chandnani P. Evaluation of effect of COVID 19 pandemic on voluntary blood donors and their donation practices: A survey based cross sectional study. Glob J Transfus Med 2021;6:245-6.
  15. Chauhan N, Chahar AS, Dua S, Mohan Y, Arora S, Agrawal A, et al. Comparison of indigenous enzyme linked immunosorbent assay and chemiluminescent immunoassays for screening for immunoglobulin G antibodies against SARS CoV 2 in India. Glob J Transfus Med 2021;6:224-7.
  16. Shaw B, Wood E, McQuilten Z, Callum J, Romon I, Sanroma P, Garcia D, Crispin PJ, Castilho L, Kutner JM, Yokoyama APH, Bravo A, Sanchez EF, Maldonado Silva K, Arora S et al. International Forum on Home-Based Blood Transfusion: Summary. Vox Sang. 2021 Oct 25. doi: 10.1111/vox.13200. Epub ahead of print. PMID: 34697808.
  17. Shaw B, Wood E, McQuilten Z, Callum J, Romon I, Sanroma P, Garcia D, Crispin P, Castilho L, Kutner JM, Yokoyama APH, Bravo A, Sanchez EF, Silva KM, Arora S et al. International Forum on Home-Based Blood Transfusion: Responses. Vox Sang. 2021 Oct 25. doi: 10.1111/vox.13199. Epub ahead of print. PMID: 34697811.
  18. Bisht A, Marwaha N, Arora S, Patidar GK, Chhabra R. National blood donor vigilance programme of India: Analysis of donor adverse reactions reported during initial 2 years of implementation (2016 and 2017). Asian J Transfus Sci. 2021 Jan-Jun;15(1):1-11. doi: 10.4103/ajts.ajts_195_20. Epub 2021 Jun 12. PMID: 34349450; PMCID: PMC829443
  19. Arora S, Dua S, Radhakrishnan N, Singh S, Madan J, Nath D. Autoimmune hemolytic anemia in children: Clinical presentation and treatment outcome. Asian J Transfus Sci 2021;15:160-5.
  20. Al-Riyami AZ, Masser B, Herczenik E, Arora S, Boateng LA, Dinardo CL, Hutchinson T, Ji Y, Langi Sasongko S, Tung JP, Panchatcharam SM; ISBT Young Professional Council. Psychological impact of the COVID-19 pandemic on young professionals in blood banks and transfusion services: A global cross-sectional survey. Vox Sang. 2022 Jan 12. doi: 10.1111/vox.13236. Epub ahead of print. PMID: 35023178.

Contact Details

Email: bloodbankssph@gmail.com

Future Plans

  1. The department aims of adding an additional layer of safety to blood and blood components by introduction of Nucleic Acid Amplification Testing (NAT) for Transfusion Transmitted Infection screening.
  2. To initiate certificate courses for Paediatric Transfusion Medicine for post graduate students and paramedical personnel’s.
  3. The department aims to establish a state of art GMP standard Cellular Therapy Lab for Hematopoietic Stem Cell Transplant and research in Cellular Medicine